Sunday 8 March 2015

Teixobactin

A team of scientists (from the US biotechnology company NovoBiotic Pharmaceuticals) reveals the results of his research on antibiotic called teixobactina. It is created from the soil where there are bacteria. The drug kills gram-positive bacteria and they do not cause an immediate resistance.
There has always been the problem that bacteria are "immunized" of antibiotics as microorganisms have evolved to resist them. So the teixobactina is a breakthrough for medicine because to bacteria it will be difficult to combat it.
It used to be impossible to grow bacteria out of their environment, but these researchers developed a membrane that 'cheated' bacteria and made them believe that they were in their natural environment when they were in a laboratory. This can lead to complicated natural ways to cure diseases like cancer.
It has not yet been tested in humans yet (it has been tested on mice and is effective), and it is too early to make it available.
It is expected that bacteria take more than 30 years to create genetic resistance to teixobactina . It is due because it inhibits the synthesis of peptidoglycan of the cell wall . That is why, researchers thought that the target could be a lipid, because when Teixobactine links up to lipids, bacteria can not continue to form the wall, and finally debilitate the organism and dies.
The drawback is that Teixobactine only works on gram-negative bacteria, which have an additional cell wall on the membrane and make them resistant to this antibiotic. But after overcome the obstacle of growing microorganisms in laboratories, it is possible that appear an effective compound against these bacteria and help to find future cures.
News link

I've been looking for articles about biology and medicine and I found this very interesting story. I was surprised because it is a recent discovery and that means that the field of medicine continues advancing and providing much help to present and future illnesses (although it is true that it passed a lot of time since the last injection of medicine to society) .

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